Department of Medicinal Chemistry

Discovering and developing new therapeutic agents and targets

Medicinal chemistry, a multidisciplinary field integrating chemistry and the life sciences, applies chemical principles to study biologically active substances such as therapeutically useful drugs, natural products, toxins and drugs of abuse. Our department offers advanced training in drug design and discovery, emphasizing areas such as cardiovascular drugs, central nervous system agents, antimicrobial targets, natural product biosynthesis, anti-cancer agents and biomolecule structure elucidation. With state-of-the-art molecular modeling facilities, synthetic organic chemistry laboratories, X-ray crystallographic equipment and high-field nuclear magnetic resonance spectrometers, our research is supported by cutting-edge technologies and collaborations with the Center for Drug Discovery.

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Degree Offerings

Our M.S. and Ph.D. programs offer an in-depth study of synthesizing, analyzing and designing pharmaceutical compounds.

Two current students celebrate the graduation of their Medicinal Chemistry peer at the Hooding and Diploma Ceremony while another graduate and their professor and mentor take photos of them posing together with flowers

Research

Our department is a leader in drug discovery and development.

Postdoctoral fellow Ennian Li presents research to industry partners at the school's Research Day

Courses

Review a list of medicinal chemistry courses on the VCU Bulletin site.

Students in the audience of a lecture hall share a laugh prior to the beginnning of a session at the Medicinal Chemistry Symposium

Graduate Student Association

Explore the alpha chapter of the nationally-recognized ACS MEDI Division.

Students and faculty in casual clothing gather for a teambuilding activity in a picnic shelter

Who We Are

Faculty and Staff

Meet our dedicated faculty and staff, whose expertise and commitment drive our mission and foster a dynamic learning environment.

Graduate Students

Meet our current students, who are actively contributing to cutting-edge research and advancing their fields within the department.

Alumni

Explore the achievements of our alumni, who exemplify the success and impact of our department's education and training.

Medicinal Chemistry News

Dickson Donu has published 27 research papers on a range of topics, including studies assessing the prevalence of malaria and the development of new medications to treat or prevent malaria. (Dean Hoffmeyer, Enterprise Marketing and Communications)

Nov. 19, 2025

How I found my research: Dickson Donu joins the battle against malaria

Donu, who will earn his Ph.D. from the School of Pharmacy next month, says the most fulfilling aspect of his work is the potential to make a real-world impact.

Dean K.C. Ogbonna and Associate Dean Mary Peace McRae stand on either side of graduate student poster award winners Grace Rilee and Yasir Alshehry, at the front of a lecture hall on Research Day.

Oct. 27, 2025

Ph.D. student wins poster award at VCU School of Pharmacy Research Day

Grace Rilee won one of two graduate poster awards at the recent schoolwide event.

Pharm.D. student Alice Adkins presents her research to a classmate capturing her on camera during Research Day.

Oct. 27, 2025

Students delve into discoveries at VCU School of Pharmacy Research Day 2025

Seven students earned awards for excelling academically and for presenting their findings at this year's Research Day.