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Job Openings

Position Title: Postdoctoral Research Fellow in Medicinal Chemistry and Drug Discovery

Job Description: A postdoctoral fellow position is available in the laboratory of Prof. Yan Zhang, Virginia Commonwealth University. We are seeking highly motivated synthetic organic chemists and medicinal chemists to join a comprehensive drug discovery program. Dr. Zhang’s lab is conducting highly interdisciplinary research focused on pre-clinical development of novel drug candidates, which covers chemical synthesis, medicinal chemistry, biochemical and biophysical assays, and molecular modeling. The successful candidate will be involved in design and synthesis of small molecule targeting G-protein coupled receptors. The duties will include design, synthesis, and biological characterization of novel lead compounds to develop drug candidates in treating varies types of diseases, including substance abuse and addiction, cancer, AIDS, and neurological disorders. Applicants should have a PhD degree in synthetic organic chemistry or medicinal chemistry. This position requires extensive experience in designing synthetic routes for novel compounds, solving challenging synthetic problems, and SAR analysis. Applicants also need to be able to apply NMR, HPLC, and MS methods to solve organic chemistry inquiries. Excellent oral and written communication skills in English are also required. To apply, please submit cover letter, CV, and contact information for three references combined into one PDF file by e-mail to: Contact: Yan Zhang, Associate Professor, Department of Medicinal Chemistry, Virginia Commonwealth University, Biotech I, 800 E Leigh Street, Richmond, VA 23298.

Job Posting

Several NIH-funded postdoctoral positions are immediately available in the laboratories of Professor Umesh Desai and his collaborators at VCU to study chemistry, biochemistry, analytical chemistry, biology and cancer-related biology of key natural biopolymers called glycosaminoglycans (see Glycosaminoglycans - Chemistry and Biology (Editors: Balagurunathan, Nakato and Desai), Elsevier (2015) pg 1 - 625). Applicants should have demonstrated publication record in one or more basic science areas listed above. Send a one-page cover letter; a two-page executive summary of your research accomplishments; and a max 6 page CV with names and contact information of your three referees to Mrs. Michelle Wise (   


Job Posting

A postdoctoral fellow position is available immediately at the Department of Medicinal Chemistry, Virginia Commonwealth University. Research will focus on the development of small molecules with potential utility in treating inflammatory and neurological disorders within an interdisciplinary environment.


  • Design and execute multi-step synthetic routes for the preparation of biologically active small molecules against various cellular protein targets. 
  • Sufficiently characterize final compounds and intermediates as required. 
  • Carry out literature searches relevant to the research topic, identify problems related to the research and recommend solutions.
  • Carry out literature searches relevant to the research topic, identify problems related to the research and recommend solutions. 
  • Keep good research records and produce well written and accurate reports. 
  • Participate in research discussions with members of the research teams in a highly collaborative research environment.  

A Ph.D. in organic chemistry, synthetic medicinal chemistry or related area is required. Must have a strong experience in organic synthesis and associated techniques and be familiar with standard analytical methods including HPLC, NMR, and LCMS. Knowledge/experience of molecular biology is preferred. 

 Interested candidates should submit applications in PDF via email ( and application should comprise a cover letter, CV, research accomplishments/summary, and three names of references.

 Virginia Commonwealth University is an Equal Opportunity/Affirmative Action Employer. Women and minorities are encouraged to apply.